Vascular Surgeons are using VesCell™ PAD to improve the quality of life of patients suffering from Peripheral Arterial Disease of the lower limbs by relieving debilitating symptoms such as ischemic rest pain and digital gangrene. VesCell™ PAD is a viable therapy for patients who have exhausted all other treatment options short of amputation.
Our first clinical trial patient has already been treated. Below is a description of that patient's condition before treatment, and 3 months after treatment.
Before Stem Cell Therapy
Severe Lower-Limb Ischemia, on maximal medication
Non-healing ulcer on left big toe due to low blood circulation with Ankle Brachial lndex (ABI) =
0.77 and Toe Brachial lndex (TBI) = 0.00 for 3-months. Size: 1x1.5 cm (Figure 1).
Severe Arterial Stenosis throughout left leg, knee, foot and toe
Underlying Diseases : Hypertension, Diabetes Mellitus, Coronary Artery Disease, Coronary
Artery Bypass Graft - 5 years prior (EF20% by SPECT)
After Stem Cell Therapy
Reduced ulcer size
0.5x1.3 cm -1 month post-treatment (Figure 3)
0.3x0.3 cm - 3 months post-treatment (Figure 4)
Complete healing ulcer - 4 months post-treatment
Improved coloration & temperature (Figure 2)
Ulcer color changed from pale to pink
Foot temperature increased
Increased ABI = 0.85 and TBI = 0.49 - 3 months post-treatment
CT-angiography revealed significant increase in vascularity of the left artery below the knee
All signs on the above indicated signs of blood circulation improvement